Avian influenza A H5N1: are we really sure it is a spillover?Article Published on 2023-06-012023-06-22 Journal: Pathogens and global health [Category] 조류인플루엔자, [키워드] antigenic drift antigenic shift avian influenza A Epidemic genetic drift H5N1 spillover. [DOI] 10.1080/20477724.2023.2201980 PMC 바로가기
Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preferenceArticle Published on 2022-12-012023-06-22 Journal: Virulence [Category] 조류인플루엔자, [키워드] antigenic drift antigenic shift Avian Influenza clade 2.3.4 functional balance. H5Nx [DOI] 10.1080/21505594.2022.2082672 PMC 바로가기
Mutation of D201G near the receptor binding site significantly drives antigenic drift of circulating H9N2 subtype avian influenza virusArticle Published on 2022-11-012023-06-22 Journal: Transboundary and emerging diseases [Category] 조류인플루엔자, [키워드] antigenic drift antigenicity Avian influenza virus evolution. H9N2 RBS [DOI] 10.1111/tbed.14707 PMC 바로가기
Interspecies Transmission from Pigs to Ferrets of Antigenically Distinct Swine H1 Influenza A Viruses with Reduced Reactivity to Candidate Vaccine Virus Antisera as Measures of Relative Zoonotic RiskArticle Published on 2022-10-292023-06-23 Journal: Viruses [Category] 신종인플루엔자, [키워드] antigenic drift influenza A virus pandemic preparedness Risk assessment variant zoonosis. [DOI] 10.3390/v14112398 PMC 바로가기
Greater Breadth of Vaccine-Induced Immunity in Females than Males Is Mediated by Increased Antibody Diversity in Germinal Center B CellsArticle Published on 2022-08-302023-06-14 Journal: mBio [Category] Fulltext, 신종인플루엔자, [키워드] antibody function Antibody Response antigenic drift antigenic variation H1N1 Sex difference viral immunity. [DOI] 10.1128/mbio.01839-22 PMC 바로가기
High activity of an affinity-matured ACE2 decoy against Omicron SARS-CoV-2 and pre-emergent coronavirusesOmicron SARS-CoV-2 및 사전 출현 코로나바이러스에 대한 친화성 성숙 ACE2 유인물의 높은 활성Article Published on 2022-08-252022-09-11 Journal: PLoS ONE [Category] SARS, 변종, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adeno-associated virus affinity airway angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antigenic antigenic drift binding can not clade complicate coronavirus coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 COVID-19 pandemic decoy develop drug Efficacy Evolution exceptional genetic diversity human ACE2 inhibitor intranasal intrinsic mitigate monoclonal antibody mutant nanomolar affinity Neutralizing omicron pandemic populations preparation Prophylaxis receptor Receptor-binding domain sarbecovirus sarbecovirus Sarbecoviruses SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus Spike protein the SARS-CoV-2 the spike protein therapeutic Threats Treatment Vaccine variant variants viral evolution viral genome viral spike viral strain viral strains virus virus widespread zoonotic [DOI] 10.1371/journal.pone.0271359 PMC 바로가기 [Article Type] Article
Plasmonic Fluor-Enhanced Antigen Arrays for High-Throughput, Serological Studies of SARS-CoV-2SARS-CoV-2의 높은 처리량, 혈청학적 연구를 위한 플라즈몬 형광 강화 항원 어레이Article Published on 2022-08-122022-09-11 Journal: ACS Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 96-well plate acute infection Antigen antigenic antigenic drift Bioscience Characteristics clinical sensitivity coordination COVID-19 pandemic Critical current diagnostics eight evaluate fluorescent highlight IgA IgG IgM Laboratory limitation limitations management microarray analysis microplate reader multiplex Outbreaks Patient Patient management plasmonics public health ranged reagents reminder response resulting Sample SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-CoV-2 detection SARS-CoV-2 positive patients Screening sensitivities sensitivity serological assays serological response serological studies SEROLOGICAL STUDY Serological testing serology Serology. several limitations specificity subset symptomatic used to evaluate Volume was performed were used [DOI] 10.1021/acsinfecdis.2c00086 PMC 바로가기 [Article Type] Article
A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in MiceVirion 기반 조합 백신은 쥐의 인플루엔자 및 SARS-CoV-2 질병으로부터 보호합니다Article Published on 2022-08-102022-09-11 Journal: Journal of Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] administration antigenic antigenic drift approach boost immunity breadth combination vaccine Coronaviruses disease distribution domain elicited generate Genetic IAV immunogenic incorporation independent Influenza influenza A influenza A virus influenza vaccine influenza vaccines influenza vaccines. Influenza virus influenza virus influenza viruses Longevity mice Neutralizing antibodies neutralizing antibody New pandemic Particles pathogen Pathogens platform Protein provided respiratory respiratory virus respiratory viruses robust SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant SARS-CoV-2 variants Seasonal influenza shown the SARS-CoV-2 vaccination Vaccine vaccine production Vaccines variant virus viruses [DOI] 10.1128/jvi.00689-22 PMC 바로가기 [Article Type] Article
Message in a bottle: mRNA vaccination for influenzaArticle Published on 2022-07-012023-07-10 Journal: The Journal of General Virology [Category] COVID19(2023년), [키워드] adjuvant antigenic drift Influenza mRNA vaccine strain selection universal vaccine. [DOI] 10.1099/jgv.0.001765 PMC 바로가기
A single amino acid at position 158 in haemagglutinin affects the antigenic property of Eurasian avian-like H1N1 swine influenza virusesArticle Published on 2022-07-012023-06-23 Journal: Transboundary and emerging diseases [Category] 신종인플루엔자, [키워드] antigenic drift Eurasian avian-like H1N1 SIVs G158E haemagglutinin. [DOI] 10.1111/tbed.14288 PMC 바로가기